IV Hydration Therapy- An overview

Addiction and substance abuse is undermining the very moral fabric and future of America today. In 1995 it was estimated that the cost of alcohol and other drugs reached a staggering figure of 276 billion, not including the pain and suffering of loved ones and friends. Alcoholics have an estimated decrease in life expectancy of 10-15 years, with alcohol the most frequently used and abused intoxicant and involved in 40% of all fatal motor vehicle accidents (1 and 2). By clicking here we get info about IV Hydration Therapy
Although not illegal, nicotine accounts for approximately 25 million people addicted and is the cause of 430,000 tobacco related deaths per year. The most commonly abused opiates are, heroin and methadone. It has been estimated by the National Institute of Drug Abuse that approximately 2.5 million Americans have a history of heroin abuse (3). Stimulants such as cocaine are widespread as well in America and it is estimated 72 million Americans have tried or are using or cocaine (3). Methamphetamine is growing at an unstoppable rate due to the ease of making the drug, and is now competing with cocaine as a drug of choice. Although there are numerous examples of addictive drugs in America they all show similar symptoms and qualities of craving and withdrawal conditions. The individuals at greatest risk are genetically predisposed through a neurochemical pathway that alters the minds perception of pleasure and reward. Kenneth Blum, coined the term, “Reward Deficiency Syndrome,” to relate to the neurotransmitter deficit that occurs due to use of drugs and alcohol. Although the pathways may vary, depending on the abused substance, they all show a common final neurochemical pathway in their expression of euphoria when abundant, and craving when deficient.
The important Amino-peptide neurotransmitters to date are serotonin, dopamine, GABA and the enkephalins. Dopamine specifically is the neurotransmitter of pleasure. When dopamine is in abundance, it provides a state of well-being. Although this research will focus on alcohol, there are many other substances that can alter the increase in dopamine resulting in pleasure. Other altering scenarios can be glucose, impulsive/compulsive disorders, gambling and risk-taking activities, opiates, cocaine and cigarettes.
When the brain is supplied with a substance a momentary spike in neurotransmitter activity of dopamine occurs. The body then reacts to down regulate this excessive increase by down regulating the neurotransmitter sites of production or receptor sites, or by increasing the breakdown of neurotransmitters. Because of this, the brain develops tolerance and the need for more of the drug to prevent a state of withdrawal.
The point at which addiction can occur is variable and based on the individual’s genes. Recently, the dopamine D2 receptor called the A1allele, has been known to be a greater prevalence for alcoholics, opiate or cocaine addicts.
This pleasure and reward system was discovered, by accident, in 1954 by James Otis. By mistake, Otis placed electrodes in the Para limbic system of rats. In doing so, Otis observed he could elicit a pleasure response. This response caused the rats to continuously press a lever, causing an electrical stimulation to this area even to the point of starvation. It was later noted that an increase in dopamine was being released in regions of the limbic system, specifically the nucleus accumbens and the hippocampus.
Recently, a pharmacological approach to alter these neurotransmitters and help people with reward deficiency syndrome has been found. Studies by Brown and Blum indicate that certain amino acid precursors can relieve cravings and reduce incidents of a relapse. Oral formulas have been formulated and produced with these amino acids, vitamins and minerals cofactors. Recently an intravenous pharmacological approach utilizing amino acid neurotransmitter precursors have shown to have an immediate and profound effect on craving reduction and withdrawals in 86% of the patients with no side effects noted by this researcher or by Excel treatment facility during the last two years. The intravenous amino acids, vitamins, and mineral therapy appears to augment the dopamine and serotonin levels while the body begins to return to better handling oral nutrients and neurotransmitter homeostasis.